
Background information on this month's topic
"Hypoxia, Stem Cells, and Tumor Progression"
by Dr. Simon
"Hypoxia regulation of TSC/mTOR signaling"
by Dr. Ellisen
Dr. Simon is Professor of Cell and Developmental Biology at the University of Pennsylvania School of Medicine and Investigator at the Abramson Family Cancer Research Institute. She studies the molecular mechanisms regulating oxygen homeostasis, stem cell maintenance, angiogenesis, and hematopoiesis.
Assistant Professor of Medicine at Harvard Medical School/ Massachusetts General Hospital, Dr. Leif Ellisen's work concerns the fundamental mechanisms of human epithelial tumorigenesis. We focus on the p53 gene family, members of which are among the most prominent genes in human cancer biology. The essential role of the p53 tumor suppressor is evidenced by its inactivation in more than 50% of sporadic human cancers, and by the striking tumor predisposition of patients carrying heterozygous germline p53 mutations.
Date: Thursday, May 10, 2007 5:00-7:00 PM
Location: New Research Building, Harvard Medical School
77 Avenue Louis Pasteur, Room 350
Parking: : Free parking in the lot below the New Research Building has been graciously donated. Space is limited and will be made available to participants coming from outside of the Longwood Medical Area, if requested by May 10th.
Please RSVP to amy_farber@hms.harvard.edu and indicate the number of people attending.
To RSVP / request a meeting with Celeste Simon, email Amy Farber at amy_farber@hms.harvard.edu or call the LAM Treatment Alliance at (617) 460-7339.
We appreciate your help in forwarding this announcement to relevant researchers, labs and clinicians.
Thank you for your interest and participation!
Best Regards,
David Kwiatkowski, Amy Farber and Michael Nurok
Dr. Leif Ellisen's Recommended Readings:
Dr. M Celeste Simon's Recommended Readings: